A Multicentre study of 1H MRS for the Characterisation of Low Grade Brain Tumours of Childhood
نویسندگان
چکیده
E. Orphanidou-Vlachou, D. Auer, J. Coupland, N. P. Davies, T. Jaspan, L. McPherson, K. Natarajan, D. Saunders, Y. Sun, T. Arvanitis, R. Grundy, and A. Peet University of Birmingham, Birmingham, United Kingdom, Birmingham Children's Hospital, Birmingham, United Kingdom, University of Nottingham, Nottingham, United Kingdom, Nottingham University Hospital, Nottingham, United Kingdom, University Hospital Birmingham, Birmingham, United Kingdom, Great Ormond Street Hospital, London, United Kingdom
منابع مشابه
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr). In this work, we studied the metabolism of glioma tumours by in vitro proton magnetic resonance spectroscopy (1H-MRS)....
متن کاملDetection of Glioblastoma Multiforme Tumor in Magnetic Resonance Spectroscopy Based on Support Vector Machine
Introduction: The brain tumor is an abnormal growth of tissue in the brain, which is one of the most important challenges in neurology. Brain tumors have different types. Some brain tumors are benign and some brain tumors are cancerous and malignant. Glioblastoma Multiforme (GBM) is the most common and deadliest malignant brain tumor in adults. The average survival rate for peo...
متن کاملClinical evaluation of a fully automated Computer Aid Decision System (CADS) for brain tumour supported diagnosis. eTUMOUR project FP6-2002-LSH-503094
Introduction In vivo 1H MRS can provide significant metabolic information for supporting the diagnosis of different types of cancers, like brain, breast, prostate, colon and ovarian tumours among others. However, the added value of MRS strongly depends on a minimum expertise in processing and analyzing MRS spectra. Although this condition can be easily achieved in medical centres with multidisc...
متن کاملDynamic 1H-MRS assessment of brain tumors: a novel approach for differential diagnosis of glioma.
PURPOSE To determine whether the changes of [Cho/NAA] ratio in patients with glioma, measured by dynamic 1H-MRS can be used to differentiate between high-grade and low-grade gliomas. MATERIALS AND METHODS This prospective study was approved by the institutional ethics committee. Written informed consent was obtained. Forty-nine patients with biopsy-proven glioma and 20 normal control subjects...
متن کاملAbstract—Many approaches have been considered for automatic grading of brain tumours by means of pattern recognition with magnetic resonance spectroscopy (MRS). Providing an improved technique which can assist clinicians in accurately identifying brain tumour grades
Many approaches have been considered for automatic grading of brain tumours by means of pattern recognition with magnetic resonance spectroscopy (MRS). Providing an improved technique which can assist clinicians in accurately identifying brain tumour grades is our main objective. The proposed technique, which is based on the discrete wavelet transform (DWT) of whole-spectral or subspectral info...
متن کامل